First Author | Transy C | Year | 1987 |
Journal | J Exp Med | Volume | 166 |
Issue | 2 | Pages | 341-61 |
PubMed ID | 3036997 | Mgi Jnum | J:8766 |
Mgi Id | MGI:57231 | Doi | 10.1084/jem.166.2.341 |
Citation | Transy C, et al. (1987) A low polymorphic mouse H-2 class I gene from the Tla complex is expressed in a broad variety of cell types. J Exp Med 166(2):341-61 |
abstractText | We have previously described the isolation of pH-2d-37, a cDNA clone that encodes a so far unknown, poorly polymorphic, class I surface molecule. We report here the isolation of the corresponding gene, its nucleotide sequence, and its localization in the Tla region of the murine MHC. Using a RNase mapping assay, we have confirmed that the second domain coding region of the 37 gene displays very limited polymorphism, and that the gene is transcribed in a broad variety of cell types, in contrast to the genes encoding the known Qa and TL antigens. Possible functions are discussed. |