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Publication : Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis.

First Author  Endo K Year  1997
Journal  Dev Growth Differ Volume  39
Issue  3 Pages  399-403
PubMed ID  9227906 Mgi Jnum  J:41881
Mgi Id  MGI:894588 Doi  10.1046/j.1440-169x.1997.00015.x
Citation  Endo K, et al. (1997) Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis. Dev Growth Differ 39(3):399-403
abstractText  A new mouse gene Mdes has been identified, which has a significant sequence homology with a Drosophila gene degenerative spermatocyte (des) that is required for the initiation of meiosis in spermatogenesis. The expression pattern of the Mdes transcript during mouse spermatogenesis is similar to that of the des transcript curing Drosophila spermatogenesis. Based on these results, it is proposed that the products of Mdes and des have a phylogenetically conserved role in vertebrate and invertebrate spermatogenesis.
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