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Publication : CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19.

First Author  Mock BA Year  1995
Journal  Genomics Volume  27
Issue  2 Pages  348-51
PubMed ID  7558004 Mgi Jnum  J:26193
Mgi Id  MGI:73858 Doi  10.1006/geno.1995.1054
Citation  Mock BA, et al. (1995) CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19. Genomics 27(2):348-51
abstractText  Helix-loop-helix proteins contain stretches of DNA that encode two amphipathic alpha-helices joined by a loop structure and are involved in protein dimerization and transcriptional regulation essential to a variety of cellular processes. CHUK, a newly described conserved helix-loop-helix ubiquitous kinase, was mapped by somatic cell hybrid analyses to human Chr 10q24-q25. Chuk and a related sequence, Chuk-rs1, were mapped to mouse chromosomes 19 and 16, respectively, by a combination of somatic cell hybrid, recombinant inbred, and backcross analyses.
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