| First Author | Xu C | Year | 1993 |
| Journal | DNA Cell Biol | Volume | 12 |
| Issue | 6 | Pages | 517-25 |
| PubMed ID | 8329119 | Mgi Jnum | J:13308 |
| Mgi Id | MGI:61509 | Doi | 10.1089/dna.1993.12.517 |
| Citation | Xu C (1993) cDNA cloning of a mouse factor that activates transcription from a metal response element of the mouse metallothionein-I gene in yeast. DNA Cell Biol 12(6):517-25 |
| abstractText | A cDNA that encodes a mouse factor that activates expression from a metal response element of the mouse metallothionein-I gene has been isolated by complementation cloning in yeast cells. The cDNA encodes a peptide with a maximum length of 99 amino acids that includes a single zinc finger sequence. In yeast cells, the cloned factor induces transcription from the metal response element in a sequence-specific but metal-independent fashion. The cDNA hybridizes to a 550-base mRNA that is constitutively expressed in mouse tissue culture cells. The ability of the mouse factor to activate transcription in yeast cells is dependent upon the carbon source. |
