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Publication : Structure of the mouse serum amyloid P component gene.

First Author  Nishiguchi S Year  1988
Journal  Biochem Biophys Res Commun Volume  155
Issue  3 Pages  1366-73
PubMed ID  3263126 Mgi Jnum  J:53830
Mgi Id  MGI:1333535 Doi  10.1016/s0006-291x(88)81292-0
Citation  Nishiguchi S, et al. (1988) Structure of the mouse serum amyloid P component gene. Biochem Biophys Res Commun 155(3):1366-73
abstractText  A genomic DNA clone corresponding to the mouse serum amyloid P component (SAP) has been isolated and characterized for the first time. The numbers of exons, the relative sites of intron/exon junctions, and the size of the coding region for mature SAP protein are all in complete agreement with those of the human SAP gene. In the 5'-flanking region of the mouse SAP gene, there is a small DNA segment (43-base pairs) which is highly homologous with the corresponding region of the human SAP gene. However, most parts of the 5'-flanking regions are not conserved between the mouse and human SAP genes, and several phorbol ester-responsive element-like sequences are present only in the mouse SAP gene.
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