| First Author | Chang AC | Year | 1998 |
| Journal | Mol Cell Endocrinol | Volume | 141 |
| Issue | 1-2 | Pages | 95-9 |
| PubMed ID | 9723890 | Mgi Jnum | J:49098 |
| Mgi Id | MGI:1276668 | Doi | 10.1016/s0303-7207(98)00097-5 |
| Citation | Chang AC, et al. (1998) Identification of a second stanniocalcin cDNA in mouse and human: stanniocalcin 2. Mol Cell Endocrinol 141(1-2):95-9 |
| abstractText | It has recently been shown that mammals contain a gene encoding a protein that is related to stanniocalcin (STC), a hormone previously considered to be present only in bony fish where it plays a major role in Ca2+ homeostasis. Here we report the identification in the mouse and human of a cDNA, STC-2, that shows significant similarity to the first mammalian STC (which we now rename STC-1). Northern analysis revealed that mammalian STC-2, like STC-1, is expressed in a wide variety of tissues. In contrast to STC-1, the predicted amino acid sequence of STC- 2 contains a cluster of histidine residues in the C-terminal portion of the protein, which suggests that STC-2 may interact with metal ions. |
