| First Author | Christiansen JH | Year | 1995 |
| Journal | Mech Dev | Volume | 51 |
| Issue | 2-3 | Pages | 341-50 |
| PubMed ID | 7547479 | Mgi Jnum | J:26524 |
| Mgi Id | MGI:73969 | Doi | 10.1016/0925-4773(95)00383-5 |
| Citation | Christiansen JH, et al. (1995) Murine Wnt-11 and Wnt-12 have temporally and spatially restricted expression patterns during embryonic development. Mech Dev 51(2-3):341-50 |
| abstractText | The Wnt gene family encodes a set of signalling molecules implicated in the development of a wide range of organisms. We have recently cloned partial cDNA sequences of murine Wnt-11 and Wnt-12. Here, we describe the spatio-temporal expression patterns of both genes during mouse embryogenesis. Wnt-11 expression is first detected within the truncus arteriosus from 8.25 dpc. By 9.5 dpc, Wnt-11 expression is detected in the somites at the medial junction of the dermatome and the myotome. Wnt-11 transcripts are also detected in limb bud mesenchyme from the time the bud is first visible. Wnt-12 is detected in the apical ectodermal ridge from 10.5 dpc. The implications of these expression patterns are discussed. |
