| First Author | Vanetti M | Year | 1992 |
| Journal | FEBS Lett | Volume | 311 |
| Issue | 3 | Pages | 290-4 |
| PubMed ID | 1397330 | Mgi Jnum | J:3081 |
| Mgi Id | MGI:51596 | Doi | 10.1016/0014-5793(92)81122-3 |
| Citation | Vanetti M, et al. (1992) Cloning and expression of a novel mouse somatostatin receptor (SSTR2B). FEBS Lett 311(3):290-4 |
| abstractText | A mouse somatostatin (SS) receptor cDNA was cloned from neuroblastoma x glioma (NG108-15) cells. The sequence is almost identical to that of the mouse SSTR2 receptor [(1992) Proc. Natl. Acad. Sci. USA 89, 251)] but lacks about 300 nucleotides between transmembrane domain VII and the C-terminus. This spliced variant of SSTR2 (designated SSTR2B) encodes a protein which is 23 residues shorter than that predicted from the SSTR2 sequence, and differs in 15 amino acids at the C-terminus. mRNA corresponding to SSTR2B occurs in mouse tissues in higher abundance than that of SSTR2. SSTR2B binds SS peptides with high affinity when expressed in mammalian cells. |
