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Publication : DNA sequences homologous to the Drosophila opa repeat are present in murine mRNAs that are differentially expressed in fetuses and adult tissues.

First Author  Duboule D Year  1987
Journal  Mol Cell Biol Volume  7
Issue  5 Pages  2003-6
PubMed ID  2885744 Mgi Jnum  J:65049
Mgi Id  MGI:1891623 Doi  10.1128/mcb.7.5.2003
Citation  Duboule D, et al. (1987) DNA sequences homologous to the Drosophila opa repeat are present in murine mRNAs that are differentially expressed in fetuses and adult tissues. Mol Cell Biol 7(5):2003-6
abstractText  A mouse embryonic cDNA containing two opa-like (CAX)n repeats was isolated on the basis of its cross-hybridization with a Drosophila K10 cDNA. Such repeated sequences were present in different murine mRNAs, some of which were specifically expressed during fetal life or in different adult tissues. This suggests that, as already described for Drosophila, opa-like sequences are parts of proteins involved in ontogenic or cell-type-specific functions in vertebrates. However, unlike Drosophila, such repeated sequences were not found within the murine homeo-boxes containing genes of the Hox-1 complex. PMID- 0002885744
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