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Publication : Phosphotyrosine-binding domains in signal transduction.

First Author  Yaffe MB Year  2002
Journal  Nat Rev Mol Cell Biol Volume  3
Issue  3 Pages  177-86
PubMed ID  11994738 Mgi Jnum  J:78228
Mgi Id  MGI:2183837 Doi  10.1038/nrm759
Citation  Yaffe MB (2002) Phosphotyrosine-binding domains in signal transduction. Nat Rev Mol Cell Biol 3(3):177-86
abstractText  Protein phosphorylation provides molecular control of complex physiological events within cells. In many cases, phosphorylation on specific amino acids directly controls the assembly of multi-protein complexes by recruiting phospho-specific binding modules. Here, the function, structure, and cell biology of phosphotyrosine-binding domains is discussed.
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