| First Author | Dantonel JC | Year | 1999 |
| Journal | Trends Biochem Sci | Volume | 24 |
| Issue | 9 | Pages | 335-9 |
| PubMed ID | 10470030 | Mgi Jnum | J:57525 |
| Mgi Id | MGI:1344904 | Doi | 10.1016/s0968-0004(99)01436-x |
| Citation | Dantonel JC, et al. (1999) The TBP-like factor: an alternative transcription factor in metazoa?. Trends Biochem Sci 24(9):335-9 |
| abstractText | Protein sequence analysis has revealed a family of TATA-binding-protein (TBP)-like factors (TLFs) in metazoan organisms. Modelling of the three-dimensional structure of these TLFs suggests that they form an asymmetric saddle-like structure and that, unlike TBP, TLFs might bind to DNA sequences other than classical TATA boxes. Thus, the existence of TLFs presents a challenge to the doctrine that TBP is a universal regulator of transcription in metazoans. |
