| Primary Identifier | IPR028539 | Type | Family |
| Short Name | Fer |
| description | Fer () is a tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis [, ]. In non-small cell lung cancer cells, Fer kinase expression has been linked to cell invasion and tumour metastasis []. It also acts downstream of EGFR (EGF receptor) to promote activation of NF-kappa-B and cell proliferation []. |
