Primary Identifier | IPR023521 | Type | Family |
Short Name | Pelota_arc |
description | Proteins in this entry are archaeal homologues of the eukaryotic gene pelota (DOM34 in yeast), which functions in recognising stalled ribosomes []. In eukaryotes, eRF3 and HBS1, which are homologous to the tRNA carrier GTPase EF1-alpha, respectively bind eRF1 and Pelota. In Archaea eRF1 (aRF1) and Pelota (aPelota) homologues exist, but no orthologues of eRF3 and Hbs1 have been detected. Instead, it seems that archaeal EF1-alpha (aEF1-alpha) could serve as a carrier GTPase protein for both aRF1 and aPelota onto the ribosome []. |