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Protein Domain : Translation release factor pelota, archaea

Primary Identifier  IPR023521 Type  Family
Short Name  Pelota_arc
description  Proteins in this entry are archaeal homologues of the eukaryotic gene pelota (DOM34 in yeast), which functions in recognising stalled ribosomes []. In eukaryotes, eRF3 and HBS1, which are homologous to the tRNA carrier GTPase EF1-alpha, respectively bind eRF1 and Pelota. In Archaea eRF1 (aRF1) and Pelota (aPelota) homologues exist, but no orthologues of eRF3 and Hbs1 have been detected. Instead, it seems that archaeal EF1-alpha (aEF1-alpha) could serve as a carrier GTPase protein for both aRF1 and aPelota onto the ribosome [].

0 Child Features

1 Parent Features

0 Protein Domain Regions