| Primary Identifier | IPR028416 | Type | Family |
| Short Name | SOCS4 |
| description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS4 (Suppressor of cytokine signalling 4) is the substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins []. SOCS4 and SOCS5 regulate epidermal growth factor receptor signaling []. |
