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Protein Domain : Islet cell autoantigen 1

Primary Identifier  IPR030796 Type  Family
Short Name  ICA1
description  Islet cell autoantigen 69kDa (ICA69) or islet cell autoantigen 1 was identified with a group of type 1 diabetes-related islet autoantigens []. ICA69 is enriched in the Golgi complex, and its N-terminal half contains a BAR-domain []. ICA69 forms heteromeric BAR-domain complexes with another cytosolic lipid-binding protein, PICK1. Together they are key regulators of the formation and maturation of insulin granules [].

0 Child Features

1 Parent Features

9 Protein Domain Regions