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Protein Domain : Stonin-2, N-terminal

Primary Identifier  IPR022699 Type  Domain
Short Name  Stonin2_N
description  Stonin 2 is involved in clathrin mediated endocytosis []. It binds to Eps15 by its highly conserved NPF motif. The complex formed has been shown to directly associate with the clathrin adaptor complex AP-2, and to localize to clathrin-coated pits (CCPs) []. In addition, stonin2 was recently identified as a specific sorting adaptor for synaptotagmin, and may thus regulate synaptic vesicle recycling []. This entry represents the N-terminal domain of stonin-2. It is found in association with .

0 Child Features

0 Parent Features

5 Protein Domain Regions