Primary Identifier | IPR022699 | Type | Domain |
Short Name | Stonin2_N |
description | Stonin 2 is involved in clathrin mediated endocytosis []. It binds to Eps15 by its highly conserved NPF motif. The complex formed has been shown to directly associate with the clathrin adaptor complex AP-2, and to localize to clathrin-coated pits (CCPs) []. In addition, stonin2 was recently identified as a specific sorting adaptor for synaptotagmin, and may thus regulate synaptic vesicle recycling []. This entry represents the N-terminal domain of stonin-2. It is found in association with . |