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Protein Domain : Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain

Primary Identifier  IPR032629 Type  Domain
Short Name  DCB_dom
description  This is theN-terminal domain of Mon2- and BIG1-like proteins, the dimerisation and cyclophilin-binding domain (DCB) [, ]. The N terminus of Mon2 (Ysl2) binds to Arf-Like small GTPase Arl1, and shows homology to brefeldin A-inhibited guanine-exchange factor (BIG) domains []. Mon2 and BIG1-like proteins play an important role in membrane traffic and Golgi homeostasis [, , ]. This domain is sufficient for targeting BIG1 to the Golgi.

0 Child Features

0 Parent Features

16 Protein Domain Regions