Primary Identifier | IPR032768 | Type | Domain |
Short Name | GTSE1_N |
description | This entry represents the N terminus of GTSE1 proteins. GTSE-1 (G2 and S phase-expressed-1) protein is specifically expressed during S and G2 phases of the cell cycle. It is mainly localised to the microtubules and when overexpressed delays the G2 to M transition. the full protein negatively regulates p53 transactivation function, protein levels, and p53-dependent apoptosis [, ]. This domain is found in eukaryotes, and is approximately 140 amino acids in length. There is a conserved FDFD sequence motif. |