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Protein Domain : Transcription factor Sp4

Primary Identifier  IPR030453 Type  Family
Short Name  SP4
description  Specificity protein 4 (Sp4) belongs to the Sp family of transcription factors that regulate expression of genes implicated in a variety of biological processes.Sp4 is highly expressed in neurons []where it mediates the coupling of neuronal activity and energy generation []. Sp4 regulates the developmental patterning of dendrites, contributes to complex processes including learning and memory, and has been linked to psychiatric disorders such as schizophrenia and bipolar disorder [, , , , , ]. It is also required for normal growth and male fertility in mice [].

0 Child Features

0 Parent Features

9 Protein Domain Regions