Primary Identifier | IPR040371 | Type | Family |
Short Name | RMC1 |
description | RMC1 is a componement of the the CCZ1-MON1 complex, which functions as a guanine exchange factor (GEF) for RAB7 during endocytic and autophagic flux to the lysosome. It positively regulates CCZ1-MON1 function that is necessary for endosomal/autophagic flux and efficient RAB7 localization on CD63-positive vesicle membranes []. |