Primary Identifier | IPR011860 | Type | Family |
Short Name | Rib-5-P_Isoase_Actino |
description | This family is a member of the RpiB/LacA/LacB family. It includes ribose 5-phosphate isomerases and D-erythrulose-4-phosphate isomerases []. The only candidates for ribose 5-phosphate isomerase in the Actinobacteria are members of this family [, ].Ribose 5-phosphate isomerase () forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes). |