| Primary Identifier | IPR001774 | Type | Domain |
| Short Name | DSL |
| description | Ligands of the Delta/Serrate/lag-2 (DSL) family and their receptors, members ofthe lin-12/Notch family, mediate cell-cell interactions that specify cell fate in invertebrates and vertebrates. In Caenorhabditis elegans, two DSL genes, lag-2 and apx-1,influence different cell fate decisions during development []. Molecular interaction between Notch and Serrate, another EGF-homologous transmembrane protein containing a region of striking similarity to Delta, has been shown and the same two EGF repeats of Notch may also constitute a Serrate binding domain [, ]. |
