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Protein Domain : Death domain-containing protein CRADD

Primary Identifier  IPR037939 Type  Family
Short Name  CRADD
description  CRADD (Caspase and RIP adaptor, also known as RAIDD) is an adaptor protein that together with the p53-inducible protein PIDD and caspase-2, forms the PIDDosome complex, which is required for caspase-2 activation and plays a role in mediating stress-induced apoptosis []. It contains an N-terminal CARD, which interacts with the caspase-2 CARD, and a C-terminal Death domain (DD), which interacts with the DD of PIDD [].

0 Child Features

0 Parent Features

5 Protein Domain Regions