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Allele : Brca1<tm1Aash> breast cancer 1, early onset; targeted mutation 1, Alan Ashworth
Primary Identifier  MGI:3706167 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Brca1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 22-24 were replaced with a floxed sequence containing cDNA for exons 22-24 with an in frame myc epitope and a bovine growth hormone poly A sequence. This vector allows conditional excision of the second, terminal BRCT domain. Downstream of the floxed sequence, a splice acceptor and PGK-neo were inserted.
  • mutations:
  • Insertion
  • synonyms:
  • Brca1<F22-24>,
  • Brca1<F22-24>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele




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