Primary Identifier | MGI:2655542 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Fn1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The floxed genomic fragment containing a modified EDA exon was excised from Fn1tm1Feb via in vivo cre mediated recombination in the germline. RNase protection and RT-PCR analysis showed that while transcripts encoding other isoforms were transcribed from the mutant allele, the EDA exon was constituitively excluded in homozygous mutant mice. |