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Allele : Fn1<tm2Feb> fibronectin 1; targeted mutation 2, Francisco E Baralle

Primary Identifier  MGI:2655542 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Fn1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The floxed genomic fragment containing a modified EDA exon was excised from Fn1tm1Feb via in vivo cre mediated recombination in the germline. RNase protection and RT-PCR analysis showed that while transcripts encoding other isoforms were transcribed from the mutant allele, the EDA exon was constituitively excluded in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Eda-Fn<->,
  • EDA<->,
  • Fn-EIIIA<->,
  • Fn-EIIIA<->,
  • EDA<->,
  • Eda-Fn<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

26 Publication categories

Trail: Allele