| First Author | Wu M | Year | 2000 |
| Journal | Genomics | Volume | 67 |
| Issue | 2 | Pages | 228-31 |
| PubMed ID | 10903848 | Mgi Jnum | J:63605 |
| Mgi Id | MGI:1861284 | Doi | 10.1006/geno.2000.6236 |
| Citation | Wu M, et al. (2000) An integrated deletion and physical map encompassing l71Rl, a chromosome 7 locus required for peri-implantation survival in the mouse. Genomics 67(2):228-31 |
| abstractText | l71Rl, a locus that maps just proximal to the pink-eyed dilution (p) locus in mouse chromosome 7, was initially identified as being required for early post-implantation survival. We define further the null phenotype of l71Rl as peri-implantation lethal, with homozygous mutant embryos degenerating between embryonic day 4.5 (E4.5) and E5. 5. We constructed an integrated deletion/physical map covering a 1. 82-Mb chromosomal segment extending proximally from p. This map defines the minimum critical interval for l71Rl as an 80- to 300-kb region. This sequence-ready deletion/physical map should enable the cloning and characterization of the l71Rl gene(s). Copyright 2000 Academic Press. |
