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Allele : Arhgef3<em1Chej> Rho guanine nucleotide exchange factor 3; endonuclease-mediated mutation 1, Jie Chen

Primary Identifier  MGI:6712019 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Arhgef3
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  TALEN mediated recombination created a 17 bp deletion in exon 3 resulting in a frameshift mutation and premature stop codons. Transcript levels are reduced in muscle tissue from homozygous mice and these transcripts are predicted to produce a protein consisting of only a small portion of the N terminus.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories