Primary Identifier | MGI:6712019 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Arhgef3 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | TALEN mediated recombination created a 17 bp deletion in exon 3 resulting in a frameshift mutation and premature stop codons. Transcript levels are reduced in muscle tissue from homozygous mice and these transcripts are predicted to produce a protein consisting of only a small portion of the N terminus. |