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Allele : Brca1<tm1Brn> breast cancer 1, early onset; targeted mutation 1, Anton Berns

Primary Identifier  MGI:3696057 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Brca1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were introduced into introns 3 and 13 to flox exons 5 through 13. A neo cassette, inserted as a selectable marker, was removed following a cross to a cre deletor strain (Tg(CMV-cre)1Cgn mice). Southern blot analysis was used to confirm genomic modifications.
  • mutations:
  • Insertion
  • synonyms:
  • Brca1<tm2Brn>,
  • Brca1<F>,
  • Brca1<tm2Brn>,
  • Brca1<F5-13>,
  • Brca1<loxP>,
  • Brca1<loxP>,
  • Brca1<F5-13>,
  • Brca1<F>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

47 Publication categories