Primary Identifier | MGI:3696057 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Brca1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were introduced into introns 3 and 13 to flox exons 5 through 13. A neo cassette, inserted as a selectable marker, was removed following a cross to a cre deletor strain (Tg(CMV-cre)1Cgn mice). Southern blot analysis was used to confirm genomic modifications. |