Primary Identifier | MGI:5013470 | Allele Type | Targeted |
Gene | Bmx | Transmission | Germline |
Strain of Origin | BALB/c | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotides substitutions in exon 14 result in the amino acid substitution of arginine for lysine at position 421 (K421R). This mutation responds to the human mutation K445R that results in the loss of kinase activity. A floxed neo cassette was removed by cre-mediated recombination. |