Primary Identifier | MGI:3028853 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ripk3 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A sequence fragment encompassing exons 1 through 3 was replaced with a loxP site flanked neomycin resistance gene cassette. Protein was undetected by Western blot analysis of homozygous mutant MEFs, bone marrow-derived macrophages, B and T lymphocytes, and thymocytes. |