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Allele : Ace<tm7Keb> angiotensin I converting enzyme; targeted mutation 7, Kenneth E Bernstein

Primary Identifier  MGI:3783350 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Ace
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The neomycin resistance gene cassette followed by cardiac specific alpha-myosin heavy chain promoter was inserted between the endogenous somatic promoter and exon 1. ACE activity and protein expression was markedly increased in heart but virtually undetectable in kidney of homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • ACE.8,
  • ACE.8
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories