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Allele : Lats2<tm1Raz> large tumor suppressor 2; targeted mutation 1, Razqallah Hakem

Primary Identifier  MGI:3056530 Allele Type  Targeted
Gene  Lats2 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Serine 371 was replaced with an in-frame stop codon followed by an inverted neomycin cassette via homologous recombination, disrupting translation of the carboxy-terminal kinase domain. Western and Northern analysis confirms absence of full-length or a shorter Lats2 peptide and presence of a longer mRNA.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele