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Allele : Postn<tm2.1(cre/Esr1*)Jmol> periostin, osteoblast specific factor; targeted mutation 2.1, Jeffery Molkentin

Primary Identifier  MGI:5908450 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Postn
Transmission  Germline Strain of Origin  129S6/SvEvTac
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  Tamoxifen-inducible cre recombinase (MerCreMer: cre recombinase fused to two modified estrogen receptor ligand binding domains at both ends) cDNA was introduced, in-frame, to the ATG start site of exon 1 via homologous recombination. The plasmid also contains a diptheria toxi A cDNA and a FRT-flanked neomycin cassette for negative and positive selection. Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Postn-MerCreMer,
  • Postn-MerCreMer,
  • Postn<MCM>,
  • Postn<MCM>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

21 Publication categories

Trail: Allele