First Author | Armstrong JF | Year | 1998 |
Journal | Br J Cancer | Volume | 78 |
Issue | 4 | Pages | 484-5 |
PubMed ID | 9716031 | Mgi Jnum | J:49159 |
Mgi Id | MGI:1276789 | Doi | 10.1038/bjc.1998.519 |
Citation | Armstrong JF, et al. (1998) Inbreeding abolishes the effect of parental origin of a mutant Rb-1 allele on pituitary tumorigenesis in mice. Br J Cancer 78(4):484-5 |
abstractText | The previously reported earlier onset of pituitary tumours in cross-bred mice inheriting a mutant Rb-1 allele paternally has been ascribed to imprinting of an Rb-1- linked gene. Here, we demonstrate that, as predicted from this mechanism, there is no effect of the parent of origin of the mutation in inbred mice. |