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Allele : Qki<tm1Imeg> quaking, KH domain containing RNA binding; targeted mutation 1, Institute of Molecular Embryology and Genetics

Primary Identifier  MGI:3033861 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Qki
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Part of intron 1 and the first part of the coding sequence in exon 2, which includes the initiation sequence and the codons for the first 44 amino acids, were replaced with an IRES and a betageo fusion gene. This removes the highly conserved QUA1 domain in the encoded protein. Absence of transcription of the endogenous gene was demonstrated by RT-PCR. Beta-galactosidase is expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • qkI<->,
  • qkI<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele