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Allele : Rad50<tm2.1Flv> RAD50 double strand break repair protein; targeted mutation 2.1, Richard A Flavell
Primary Identifier  MGI:4837633 Allele Type  Targeted
Gene  Rad50 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  In ES cells containing Rad50tm1Flv, which lacks DNaseI hypersensitive site 7 (RHS7), floxed neo cassette replaces DNaseI hypersensitive site 4 and 5 (RHS4,5) between exon 21 and exon 22. Cre mediated recombination removed the neo cassette leaving the remaining DNaseI hypersensitive site 6 (RHS6) in intron 21 and exons 22 through 24 floxed. Western blot analysis confirmed normal protein expression.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • RHS4,5,7<->,
  • RHS457,
  • RHS4,5,7<->,
  • RHS457
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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