| Primary Identifier | MGI:2676007 | Allele Type | Targeted |
| Attribute String | Modified isoform(s), Reporter | Gene | Ablim1 |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Elimination of the retina-specific L isoform was accomplished by replacing all of exon 1 and 18 bp of intron 1 with a cassette containing IRES-lacZ and MC1-neo. RT-PCR analysis of homozygous mutant mice showed that while transcripts encoding the M and S isoforms were present, transcript encoding the L isoform was absent. Reporter expression was observed but sporadic. |
