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Allele : Mon2<em1(IMPC)J> MON2 homolog, regulator of endosome to Golgi trafficking; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6163850 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Mon2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 4 guide sequences GTAGATGCTCAAAAAACTGG, AGTGTTCAGGCATTCCACCG, GAACTGATTTTATTTCCCAG and GTGTTGTGTGTGCCACTACT, which resulted in a 388 bp deletion beginning at Chromosome 10 position 123,059,114 bp and ending after 123,059,501 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000419243 (exon 2) and 324 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 37 and early truncation 1 amino acid later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories