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Allele : Ccne1<tm1Jro> cyclin E1; targeted mutation 1, James M Roberts

Primary Identifier  MGI:3584133 Allele Type  Targeted
Attribute String  Not Specified Gene  Ccne1
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance cassette was inserted into intron 10 and sequence in exon 11 encoding amino-acid residue 393 was mutated from Thr to Ala (ACA to GCA) preventing phosphorylation of this residue. Heterozygotes were crossed with carriers of Meox2tm1(cre)Sor, excising the neomycin resistance cassette and leaving the T393A point mutation.
  • mutations:
  • Single point mutation
  • synonyms:
  • E<T393A>,
  • E<T393A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele