Primary Identifier | MGI:2384164 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cdkn2a |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This allele was generated by breeding mice carrying Cdkn2atm2Brn with transgenic mice expressing cre. The expression of cre recombinase resulted in the excision of exons 2 and 3. The deletion of this region affects the expression of both isoforms, p16Ink4a and p19ARF. |