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Allele : Del(16Tmprss2-Erg)1Sho deletion, Chr 16, Stuart Orkin 1

Primary Identifier  MGI:5578624 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(16Tmprss2-Erg)1Sho
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination between Ergtm1.1Sho and Tmprss2tm3Sho results in a 3 MB deletion and creates a fusion product between the end points that recapitulates a gene fusion frequently observed in patients with prostate cancer.
  • mutations:
  • Intragenic deletion,
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • T-delta-Erg,
  • Del1Sho,
  • T-delta-Erg,
  • Del1Sho
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1 Feature

Genome

0 Expresses

31 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories