Primary Identifier | MGI:4941319 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Tert-cre/ERT2)1Brlt |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cre/ERT2 cassette was cloned into a vector containing 4.4 kb of the murine Tert promoter. The linearized construct was electroporated into J1 ES cells for integration. 3 clones were selected for blastocyst injection and three chimeras were generated. One line containing 10 copies of the transgene was selected for further analysis. |