First Author | Krause KH | Year | 1997 |
Journal | Int J Vitam Nutr Res | Volume | 67 |
Issue | 6 | Pages | 461-3 |
PubMed ID | 9433681 | Mgi Jnum | J:45255 |
Mgi Id | MGI:1194701 | Citation | Krause KH, et al. (1997) Effect of biotin depletion on spike-wave seizures in the tottering mutant mouse. Int J Vitam Nutr Res 67(6):461-3 |
abstractText | Influence of depletion of biotin on spontaneously occurring spike-wave seizures in the tottering mutant mouse was tested by electrocorticographic recordings over three hours in five mice fed a biotin deficient diet. Frequency of seizures as well as percent of time with epileptic discharges were clearly lowered in the biotin deficient animals compared with eight mice of the same age under normal food (p < 0.01 in Wilcoxon's U-test). |