Primary Identifier | MGI:2387971 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ptger1 |
Transmission | Germline | Strain of Origin | DBA/1LacJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 671 bp of coding sequence were replaced by the insertion of a neomycin selection cassette into exon 2. Transcript was undetected in liver, uterus, and kidney tissue by RT-PCR analysis and in situ hybridization of kidney tissue. Western blot analysis of Prkcl1 protein expression indicated that the targeting vector did not significantly disrupt the the Prkcl1 locus, which putatively overlaps the Ptger1 locus. |