| Primary Identifier | MGI:6448353 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Ttyh1 |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a deletion of exon 4. Exon 4 deletion is predicted to result in a truncated protein of 198 amino acids thus disrupting the gene. Western blot analysis confirmed absence of TTYH1 protein but intact long non-coding RNA D030047H15Rik (NR_033548.1). qRT-PCR confirmed mRNA expression of the lncRNA. |
