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Allele : Chrne<tm2Vwi> cholinergic receptor, nicotinic, epsilon polypeptide; targeted mutation 2, Veit Witzemann

Primary Identifier  MGI:5314798 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph, Inserted expressed sequence Gene  Chrne
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA segment encoding an L221F substitution followed by a PGK-neomycin sequence was inserted. Transcriptional efficiency of the mutated allele was about 50% of the unaltered allele but end plate receptor density was unaffected.
  • mutations:
  • Insertion
  • synonyms:
  • AChR<epsilonL221F>,
  • AChR<epsilonL221F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele