Primary Identifier | MGI:5314798 | Allele Type | Targeted |
Attribute String | Humanized sequence, Hypomorph, Inserted expressed sequence | Gene | Chrne |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cDNA segment encoding an L221F substitution followed by a PGK-neomycin sequence was inserted. Transcriptional efficiency of the mutated allele was about 50% of the unaltered allele but end plate receptor density was unaffected. |