Primary Identifier | MGI:7260259 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CMV-m157)1Wyok |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This trasngene expresses m157, which is the murine cytomegalovirus (MCMV)âencoded ligand for the mouse Klra8 (Ly49H) NK cell activation receptor, under the control of a ubiquitous CMV promoter. The m157 ORF encodes a deduced 329-aa polypeptide. m157 contains a potential N-terminal 21-aa signal peptide, and an ectodomain with five potential sites for N-linked glycosylation. However, a putative hydrophobic transmembrane domain is interrupted by a stop codon. No line numbers were given. |