| Primary Identifier | MGI:7444470 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Sim1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A selection cassette containing an internal ribosomal entry sequence (IRES) linked to Cre-recombinase and an Frt-flanked neomycin resistance gene was targeted 3 bp after the stop codon of the Sim1 gene, so that Cre-recombinase expression was driven by the endogenous gene. Flpe recombinase transgene mice were then used to remove the neomycin selection cassette. |
