Primary Identifier | MGI:5431111 | Allele Type | Targeted |
Gene | Opn1sw | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 1 was replaced with one in which an A to T transition results in the amino acid substitution of tyrosine for phenylalanine at position 81 (F81Y). An FRT-flanked neo cassette was inserted downstream of exon 3. qRT-PCR confirmed a 1000-fold reduction in transcript expression. |